Most people don't believe that genetics has much to do with a person being overweight or obese; that it is much more based on the environment and conditioning you grow up with and how this effects the diet and exercise lifestyle you lead.
But scientists have recently found a gene 'CPTic' which makes a protein that protects against weight gain caused by a high-fat diet. They've only tested this on mice so far but the implications seem to be that people who lack this gene will gain much more weight than people who carry a normal level of this gene.
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The above photo is by Piddy77
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